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FDA批准25-羟基维生素D3在蛋鸡、种鸡和火鸡中作为饲料添加剂或饮水使用
双击自动滚屏 发布者:hn 发布时间:2018-11-8 阅读:531

美国食品药品监督局(FDA)正在修改25-羟基维生素D3作为动物饲料和饮水添加剂方面的法规,允许25-羟基维生素D3在蛋鸡,种鸡和火鸡中作为活性维生素D3来源。这是应DSM提出的申请而做出的修订。
25-羟基维生素D3在饲料和饮水中使用需遵循以下:
     (1)在蛋鸡、种鸡饲料中使用不能超过69ppb,饮水中不能超过34.5ppb。
     (2)在火鸡饲料中使用不能超过92ppb,在饮水中使用,对于0~3周龄火鸡不能超过25ppb,4~11周龄火鸡不能超过36ppb,11周龄以上火鸡不能超过45ppb。

原文内容如下:

The Food and Drug Administration (FDA, we, or the Agency) is amending the regulations for food additives permitted in feed and drinking water of animals to provide for the safe use of 25-hydroxyvitamin D3 as a source of vitamin D3 activity for layer and breeder chickens and turkeys. This action is in response to two food additive petitions filed by DSM Nutritional Products.
The food additive, 25-hydroxyvitamin D3, may be safely used in accordance with the following prescribed conditions:
(a) The additive is used or intended for use as a source of vitamin D3 activity in animal feed or drinking water in accordance with good manufacturing and feeding practices as follows:
(1) In feed or drinking water of layer and breeder chickens not to exceed 69 parts per billion (ppb) in feed or 34.5 ppb in drinking water.
(2) In feed or drinking water of turkeys not to exceed:
(i) 92 ppb in feed; or
(ii) In drinking water, 25 ppb for turkeys up to 3 weeks of age, 36 ppb for turkeys from 4 to 11 weeks of age, or 45 ppb for turkeys over 11 weeks of age.
(b) The additive consists of not less than 94 percent 25-hydroxyvitamin D3 (9,10-secocholesta-5,7,10(19)-triene-3b, 25-diol).
(c) The additive meets the following specifications:
(1) Not more than 1 percent of any individual sterol.
(2) Not more than 5 percent water.
(3) Not more than 20 parts per million (ppm) lead.
(4) Not more than 20 ppm aluminum.
(5) Not more than 1.0 percent solvents and non-detectable levels of 2′, 4′, 5′, 7′ tetraiodofluorescin.
(6) Not more than 1 ppb 1,25-dihydroxycholecalciferol.
(d) To assure safe use of the additive, in addition to the other information required by the Federal Food, Drug, and Cosmetic Act, the label and labeling shall contain:
(1) The name of the additive.
(2) A statement to indicate the maximum use level of 25-hydroxyvitamin D3 must not exceed 69 ppb in feed or 34.5 ppb in drinking water for layer and breeder chickens.
(3) A statement to indicate for turkeys the maximum use level of 25-hydroxyvitamin D3 must not exceed 92 ppb in feed; or in drinking water, 25 ppb for turkeys up to 3 weeks of age, 36 ppb for turkeys from 4 to 11 weeks of age, or 45 ppb for turkeys over 11 weeks of age.
(4) Adequate use directions to ensure that 25-hydroxyvitamin D3 (and all premixes) is uniformly blended throughout the feed or drinking water.
(5) An expiration date on all premix labeling.
(6) A statement on all premix labeling (feed and drinking water forms) that 25-hydroxyvitamin D3 cannot be used simultaneously in both feed and water.

 
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